Book an appointment
Schedule a visit with a board-certified doctor at a time that works best for you.
step 1
Get Prescription Lotrel Online
- Treats high blood pressure
- Prescription medication
- Contains amlodipine and benazepril
4.9
745,000+ Patients Served
What is Lotrel?
Lotrel is a prescription medication that combines two active ingredients: amlodipine and benazepril. Amlodipine is a calcium channel blocker, while benazepril is an angiotensin-converting enzyme (ACE) inhibitor.
These two medications work together to help lower high blood pressure (hypertension).
Lotrel is typically used to treat high blood pressure in people who require treatment with both a calcium channel blocker and an ACE inhibitor to achieve optimal blood pressure control. By combining these two medications into one pill, Lotrel simplifies the treatment regimen and may improve medication adherence.
How does Lotrel work?
Lotrel works through its two active ingredients, amlodipine and benazepril, to lower high blood pressure (hypertension) by targeting different mechanisms involved in blood pressure regulation.
Amlodipine works by blocking calcium channels in the blood vessels and heart muscle cells. By doing so, it stops the influx of calcium ions into these cells, leading to relaxation and dilation (widening) of the blood vessels.
This allows blood to flow more easily through the vessels.
Benazepril blocks an enzyme called ACE, which normally turns angiotensin I into angiotensin II.
Angiotensin II tightens blood vessels and increases blood pressure by releasing aldosterone – a hormone that retains salt and water. By stopping ACE and reducing angiotensin II, benazepril helps relax blood vessels, decrease fluid retention, and lower blood pressure.
By combining the effects of amlodipine and benazepril, Lotrel provides a dual-action effect to help lower blood pressure more effectively than either medication alone.
This combination therapy allows for better blood pressure control and may reduce the risk of cardiovascular events in people with hypertension.
How LifeMD works
step 2
Get the answers you need
Receive quality care, from diagnosis and prescriptions to lab orders and more.
step 3
Enjoy 24/7 peace of mind
Rest easy knowing that LifeMD is here for all your primary, urgent, and chronic health needs.
Meet our expert
My approach to healthcare is grounded in listening, education, and empowering patients to take an active role in their wellness.
I believe virtual care expands access and allows me to support patients with the same compassion and clinical excellence as an in-person visit. My goal is always to meet patients where they are and guide them toward safe, personalized, sustainable health outcomes.
Dina Whiteaker
APRN
Frequently
Asked
Questions
Is Lotrel a beta blocker?
No, Lotrel is not a beta blocker. Lotrel is a combination medication that contains two active ingredients: amlodipine and benazepril. Amlodipine is a calcium channel blocker, while benazepril is an angiotensin-converting enzyme (ACE) inhibitor.
Does Lotrel cause hair loss?
Hair loss is not a commonly reported side effect of Lotrel. However, like any medication, Lotrel can cause side effects in some people, although not everyone will experience them.
If you are experiencing hair loss or any other unusual symptoms while taking Lotrel, it's essential to consult with your healthcare provider. They can help determine if the hair loss is related to the medication or if there may be another underlying cause.
Does Lotrel cause weight gain?
Some people may experience changes in weight while taking blood pressure medications, but this is often due to factors such as fluid retention rather than actual fat gain. Additionally, individual responses to medications can vary, and some people may experience weight changes while others do not.
If you notice significant weight gain or any other unusual symptoms while taking Lotrel, it's essential to consult with your healthcare provider. They can help determine if the weight gain is related to the medication or if there may be another underlying cause.
Does Lotrel cause erectile dysfunction?
Lotrel isn't directly linked to erectile dysfunction, but health experts are still examining the potential connection between calcium channel blockers (like amlodipine) and ED.
When is the best time to take Lotrel?
Many people find it convenient to take Lotrel in the morning, either before breakfast or with breakfast, to help remember to take it regularly.
However, if you experience dizziness or lightheadedness after taking Lotrel, your healthcare provider may recommend taking it in the evening before bedtime.
Can you drink on Lotrel?
It's generally recommended to limit or avoid alcohol while taking Lotrel. Drinking alcohol can increase the risk of certain side effects associated with Lotrel, such as dizziness, lightheadedness, and fainting, especially when standing up from a sitting or lying position.
Additionally, alcohol can potentially amplify the blood pressure-lowering effects of Lotrel, leading to a more significant drop in blood pressure than intended.
What are the most common side effects of Lotrel?
The most common side effects of Lotrel include:
- Dizziness or lightheadedness
- Cough
- Swelling of the hands, ankles, or feet
- Fatigue or weakness
- Headache
- Nausea or upset stomach
- Flushing
- Hyperkalemia
It's important to note that not everyone will experience these side effects, and some people may not experience any side effects at all. If you have concerns about potential side effects or experience any unusual symptoms while taking Lotrel, contact your healthcare provider.
Can LifeMD prescribe Lotrel?
Yes! With LifeMD, you can connect with a licensed healthcare provider from the comfort of your home within an hour. If appropriate, your provider may prescribe Lotrel and send it directly to your local pharmacy.
For even more flexibility, a LifeMD+ membership gives you 24/7 access to care, same-day prescription refills, exclusive wellness perks, and easy access to lab testing — all designed to make managing your health simple and stress-free.
Skip the waiting room. Join LifeMD and take control of your health today.
Learn more
High Blood Pressure
Sleep Disorders
Heart Disease
Does High Blood Pressure Cause Fatigue?
January 30, 2023
4 min
Anxiety
Depression
Pain
High Blood Pressure
Stress
Complementary and Alternative Medicine
Exploring the Benefits and Different Techniques of Music Therapy
July 05, 2023
5 mins
High Blood Pressure
Heart Disease
How Are Hypertension, Heart Disease, and Strokes Related?
January 15, 2023
3 min
Sleep Disorders
Diabetes
Heart Disease
High Blood Pressure
Can Sleep Apnea Kill You? Dangers and Risk Factors You Need to Know
December 16, 2022
4 min
Heart Disease
High Blood Pressure
Is Tomato Juice Good for You?
June 25, 2025
4 mins